Beilstein J. Org. Chem.2014,10, 1–6, doi:10.3762/bjoc.10.1
trifluoromethylation; 19FNMRkinetics; nitration; organo-fluorine; Introduction
Since the advent of the hypervalent-iodine-based electrophilic trifluoromethylation reagents 1 and 2 in 2006 they have found widespread application in organic synthesis (Figure 1) [1][2][3][4]. Recently, increasing interest has been
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Graphical Abstract
Figure 1:
Electrophilic trifluoromethylating agents 1 and 2.